化工社化工社 化学情報印刷レポート · 研究参考用
1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl ester → cis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-methyl-5-oxo-1-pyrrolidineacetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl ester | HCID 574476 | — |
| 反応物 | 2-(cis-2,6-Dimethyl-1-piperidinyl)ethanamine | HCID 783702 | — |
| 生成物 | cis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-methyl-5-oxo-1-pyrrolidineacetamide | HCID 70610011 | — |
反応手順
From 9.26 g. of ethyl 2-methyl-5-oxo-1-pyrrolidineacetate (British Pat. No. 1,309,692) and 8.6 g. of cis-2-(2,6-dimethyl-1-piperidinyl)ethylamine, following the procedure of Example 9, there is obtained cis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-methyl-5-oxo-1-pyrrolidineacetamide; m.p. 115°-116° C. after crystallization from cyclohexane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04145347 |
| 出典データセット | uspto-grants-1979_03 |
| ORD ID | ord-88dc0e06b5634809b2f665ef092cad30 |
| 出典メモ | uspto-grants-1979_03 |