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Ethyl 2-oxopyrrolidine-1-acetate → (+/-)-N-[2-(4-methyl-1-piperazinyl)propyl]-2-oxo-1-pyrrolidineacetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 2-oxopyrrolidine-1-acetate | HCID 109094 | — |
| 反応物 | 2-(4-Methylpiperazin-1-yl)propan-1-amine | HCID 16641457 | — |
| 生成物 | (+/-)-N-[2-(4-methyl-1-piperazinyl)propyl]-2-oxo-1-pyrrolidineacetamide | HCID 21327809 | — |
反応手順
From 7.0 g. of ethyl 2-oxo-1-pyrrolidineacetate and 6.3 g. of 2-(4-methyl-1-piperazinyl)propylamine, following the procedure of Example 9, there is obtained (±)-N-[2-(4-methyl-1-piperazinyl)propyl]-2-oxo-1-pyrrolidineacetamide; m.p. 84°-85° C. after recrystallization from cyclohexane and from heptane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04145347 |
| 出典データセット | uspto-grants-1979_03 |
| ORD ID | ord-1d6feda2a2f540c69ff66a6f425f5c7a |
| 出典メモ | uspto-grants-1979_03 |