1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl ester → 2-(2-methyl-5-oxo-1-pyrrolidinyl)-N-[2-(1-piperidinyl)propyl]acetamide

HRID 614479

反応式

HRID 614479 の反応式
[CH3:1][CH:2]1[CH2:6][CH2:5][C:4](=[O:7])[N:3]1[CH2:8][C:9]([O:11]CC)=O.[N:14]1([CH:20]([CH3:23])[CH2:21][NH2:22])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH3:1][CH:2]1[CH2:6][CH2:5][C:4](=[O:7])[N:3]1[CH2:8][C:9]([NH:22][CH2:21][CH:20]([N:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1)[CH3:23])=[O:11]

参加物

3

反応物 2

HCID 5744761-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl esterHCID 124554092-(Piperidin-1-yl)propan-1-amine

生成物 1

HCID 213277832-(2-methyl-5-oxo-1-pyrrolidinyl)-N-[2-(1-piperidinyl)propyl]acetamide

実験手順

From 9.3 g. of ethyl 2-methyl-5-oxo-1-pyrrolidineacetate and 10.7 g. of 2-(1-piperidinyl)propylamine (J. Chem. Soc. 1947, 1511), following the procedure of Example 9, there is obtained (±)-2-methyl-5-oxo-N-[2-(1-piperidinyl)propyl]-1-pyrrolidineacetamide; m.p. 111°-112° C. after recrystallization from heptane.

出典と根拠

ORDレコード
ord-c5b7ab7d4a104f209d1703148255e20b
出典データセット
uspto-grants-1979_03
特許番号
US04145347

関連ノート

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