N,N-Dimethylethylenediamine → N-[2-(Dimethylamino)ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide

反応式

[O:1]=[C:2]1[CH2:6][CH2:5][CH2:4][N:3]1[CH2:7][C:8]([O:10]CC)=O.[CH3:13][N:14]([CH3:18])[CH2:15][CH2:16][NH2:17]>>[CH3:13][N:14]([CH3:18])[CH2:15][CH2:16][NH:17][C:8](=[O:10])[CH2:7][N:3]1[CH2:4][CH2:5][CH2:6][C:2]1=[O:1]

参加物

反応物 2

HCID 66053N,N-Dimethylethylenediamine

HCID 109094Ethyl 2-oxopyrrolidine-1-acetate

生成物 1

HCID 21327799N-[2-(Dimethylamino)ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide

実験手順

From 8.5 g. of ethyl 2-oxo-1-pyrrolidineacetate and 8.8 g. of 2-(dimethylamino)ethylamine, following the procedure of Example 1, there is obtained N-[2-(dimethylamino)ethyl]-2-oxo-1-pyrrolidineacetamide; b.p. 146°-147° C./0.1 mm.

出典と根拠

ORDレコード: ord-4ddba3e4142e4beaa4b9273a3b629824
出典データセット: uspto-grants-1979_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04145347

反応ノート

読み込み中…