Ammonia → HCID 21328029、化合物

HRID 614561ノート

反応式

HRID 614561 の反応式
[N+:1]([C:4]1[CH:10]=[CH:9][C:8]([S:11]([CH2:13][CH:14]=[CH2:15])=[O:12])=[CH:7][C:5]=1[NH2:6])([O-])=O.[O-]S(S([O-])=O)=O.[Na+].[Na+].N.O>C(O)C>[CH2:13]([S:11]([C:8]1[CH:9]=[CH:10][C:4]([NH2:1])=[C:5]([NH2:6])[CH:7]=1)=[O:12])[CH:14]=[CH2:15]

参加物

6

反応物 4

HCID 222AmmoniaHCID 962WaterHCID 24489Sodium Dithionite2 回HCID 21328026HCID 21328026、化合物

生成物 1

HCID 21328029HCID 21328029、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

To a suspension of 0.0075 mole of 2-nitro-5-(2-propenylsulfinyl)aniline in 75 ml of absolute ethanol under N2 there is added a solution of 4.9 g of Na2S2O4, 4.9 ml of concentrated NH3 and 30 ml of water. The mixture is refluxed for 15 minutes and an additional 0.4 g of Na2S2O4 is added. After 15 minutes of reflux the ethanol is evaporated. The aqueous residue is made basic (pH 12) and extracted with dichloromethane. The combined, dried extracts are evaporated and the resulting oily residue is used immediately in the next reaction.

後処理

  1. temperatureThe mixture is refluxed for 15 minutes
  2. customis evaporated
  3. extractionextracted with dichloromethane
  4. customdried extracts
  5. customare evaporated
  6. customthe resulting oily residue is used immediately in the next reaction

出典と根拠

ORDレコード
ord-7d3bb406570645878a9f1930c2701643
出典データセット
uspto-grants-1979_03
特許番号
US04145431

反応ノート

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