Methyl [[(methoxycarbonyl)amino](methylthio)methylene]carbamate → HCID 178502046、化合物

反応式

[CH2:1]([S:8]([C:10]1[CH:15]=[CH:14][C:13]([NH2:16])=[C:12]([NH2:17])[CH:11]=1)=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:18][O:19][C:20]([NH:22][C:23](=NC(OC)=O)SC)=[O:21]>CO.C(O)(=O)C>[CH2:1]([S:8]([C:10]1[CH:15]=[CH:14][C:13]2[NH:16][C:23]([NH:22][C:20](=[O:21])[O:19][CH3:18])=[N:17][C:12]=2[CH:11]=1)=[O:9])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

実験手順

To 3.34 g (14.5 mMol) of 4-(benzyl)sulfinyl-1,2-diaminobenzene in 35 ml methanol and 0.84 ml acetic acid is added 3.11 g (16 mMol) 1,3-bis(methoxycarbonyl)-S-methyl isothiourea, and the resulting solution heated to reflux for 3 hours. The solvent is removed in vacuo, the solid digested with water and filtered and washed with ether. The resulting solid is recrystallized from ethanol to yield the title compound.