化工社化工社 化学情報印刷レポート · 研究参考用
Formaldehyde → 1-Hydroxymethyl-3,5-dimethyl-1,2,4-triazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Formaldehyde | HCID 712 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 1H-1,2,4-Triazole, 3,5-dimethyl- | HCID 139001 | — |
| 反応物 | Sodium ethoxide | HCID 2723922 | — |
| 反応物 | 1,4-dihydroxy-N-[gamma-(2,4-di-tert-amylphenoxy)propyl]-2-naphthamide | HCID 20442411 | — |
| 反応物 | 1-Chloromethyl-3,5-dimethyl-1,2,4-triazole | HCID 21326698 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 1-Hydroxymethyl-3,5-dimethyl-1,2,4-triazole | HCID 21326697 | — |
反応手順
1-Hydroxymethyl-3,5-dimethyl-1,2,4-triazole which was prepared from 3,5-dimethyl-1,2,4-triazole and formaldehyde was reacted with 1.5 to 5 times on a molar basis of thionyl chloride to prepare 1-chloromethyl-3,5-dimethyl-1,2,4-triazole. This was reacted with an equimolar amount of 1,4-dihydroxy-N-[γ-(2,4-di-tert-amylphenoxy)propyl]-2-naphthamide in DMF in the presence of 1.5 to 3 times on a molar basis of sodium ethoxide to obtain Coupler (36).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04146396 |
| 出典データセット | uspto-grants-1979_03 |
| ORD ID | ord-1e4157c148b84269a4fe0c5d445ebf7d |
| 出典メモ | uspto-grants-1979_03 |