5-Nitro-2-Furoic Acid → Trimethyltin 5-nitro-2-furoate

関与物質

反応条件

反応手順

Trimethyltin 5-nitro-2-furoate (Compound E) was prepared by reacting trimethyltin hydroxide (9.20 g, 0.0509 mole) with 5-nitro-2-furoic acid (8.00 g, 0.0509 mole) in 75 ml benzene. The reaction mixture was refluxed for 19 hours at a temperature of 80° C. and a pressure of 1 atm. The resulting precipitate was collected on filter paper and dried to yield 15.30 g (94%) of crude trimethyltin 5-nitro-2-furoate, melting point 188.2°-195.5° C. The resulting compound was recrystallized three times from benzene to give Compound E, melting point 190°-192° C. The elemental analysis gave (in %) C:30.15, H:3.74, N:4.43, Sn:36.89, calculated for C8H11NO5Sn (in %): C:30.04, H:3.47, N:4.38, Sn:37.12.

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