化工社化工社 化学情報印刷レポート · 研究参考用
Oxalyl chloride → 2-{4-[4-(Trifluoromethyl)phenoxy]phenoxy}propanoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | Trifop | HCID 181206 | — |
| 触媒 | Dimethylformamide | HCID 6228 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 2-{4-[4-(Trifluoromethyl)phenoxy]phenoxy}propanoyl chloride | HCID 12906015 | — |
反応手順
Oxalyl chloride (1.56 g, 1.1 ml, 12.32 mmol) is added to a stirring solution of 2-[4-(4-trifluoromethylphenoxy)phenoxy]propionic acid (2.00 g, 6.16 mmol), dimethylformamide (DMF; 4 drops) and ether (50 ml). The mixture is stirred at RT for 3 hours. Insoluble material is filtered off and solvent is removed in vacuo to give 2-[4-(4-trifluoromethylphenoxy)phenoxy]propionic acid chloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04497965 |
| 出典データセット | uspto-grants-1985_02 |
| ORD ID | ord-b22259dbd0674c5cbab84b9151c284b3 |
| 出典メモ | uspto-grants-1985_02 |