Dichloromethane → HCID 12962282、化合物

HRID 616016ノート

反応式

HRID 616016 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]2[NH:14][CH2:13][CH2:12][O:11]2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].C(Cl)Cl.[Cl:18][CH:19]([Cl:23])[C:20](Cl)=[O:21]>C(N(CC)CC)C>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]2[N:14]([C:20](=[O:21])[CH:19]([Cl:23])[Cl:18])[CH2:13][CH2:12][O:11]2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]

参加物

5

反応物 3

HCID 6344DichloromethaneHCID 6593Dichloroacetyl chlorideHCID 2417432-(3-Nitrophenyl)-1,3-oxazolidine

生成物 1

HCID 12962282HCID 12962282、化合物

試薬・触媒・溶媒 1

HCID 8471Triethylamine溶媒

実験手順

Five and eight tenths grams of 2-m-nitrophenyl oxazolidine was dissolved in 50 ml. methylene chloride containing 3.5 g. of triethylamine. Dichloroacetyl chloride 4.4 g. was added dropwise with stirring to the reaction flask and cooled in a water bath at room temperature. When addition was complete, the mixture was stirred at room temperature for about 30 minutes, washed with water, separated and dried over anhydrous magnesium sulfate. The solvent was stripped off under vacuum. There was obtained a yield of 8.6 g. of the title compound, ND30 = 1.5590.

後処理

  1. additionwas added dropwise
  2. additionWhen addition
  3. stirringthe mixture was stirred at room temperature for about 30 minutes
  4. washwashed with water
  5. customseparated
  6. dry with materialdried over anhydrous magnesium sulfate
  7. customThere was obtained a yield of 8.6 g

出典と根拠

ORDレコード
ord-9e8268abcb3b4f43a5cd5366b8610003
出典データセット
uspto-grants-1978_02
特許番号
US04072688

反応ノート

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