Dichloromethane → HCID 13363479、化合物

HRID 616026

反応式

HRID 616026 の反応式
[C:1]1([CH:7]2[NH:11][CH2:10][CH:9]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[O:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(Cl)Cl.[Br:21][CH:22]([CH2:26][Br:27])[C:23](Cl)=[O:24]>C(N(CC)CC)C>[C:1]1([CH:7]2[N:11]([C:23](=[O:24])[CH:22]([Br:21])[CH2:26][Br:27])[CH2:10][CH:9]([C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=3)[O:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

5

反応物 3

HCID 6344DichloromethaneHCID 867902,3-Dibromopropanoyl chlorideHCID 20221975HCID 20221975、化合物

生成物 1

HCID 13363479HCID 13363479、化合物

試薬・触媒・溶媒 1

HCID 8471Triethylamine溶媒

実験手順

Four and five tenths grams of 2,5-diphenyl oxazolidine was dissolved in 50 ml. of methylene chloride and 5 g. of 2,3-dibromopropionyl chloride was added and the mixture stirred in an ice bath, while 2.1 g. of triethylamine was added dropwise. After standing for about 30 minutes, the mixture was washed with water, separated and dried over magnesium sulfate and stripped under vacuum. There was obtained a yield of 7.1 g. of an oil, the title compound, ND30 = 1.5734.

後処理

  1. washthe mixture was washed with water
  2. customseparated
  3. dry with materialdried over magnesium sulfate
  4. customThere was obtained a yield of 7.1 g

出典と根拠

ORDレコード
ord-e8b13900c7a349ae9ad35ea024ad1413
出典データセット
uspto-grants-1978_02
特許番号
US04072688

関連ノート

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