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Methanethiol → 5-(Methylthio)-2-nitroaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanethiol | HCID 878 | — |
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 5-Chloro-2-nitroaniline | HCID 74218 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 5-(Methylthio)-2-nitroaniline | HCID 10535482 | — |
反応手順
A mixture of 2 g. sodium hydroxide, 2.4 g. methylmercaptan and 20 ml. dimethylformamide is stirred at room temperature for two hours. 3.0 g. 2-amino-4-chloro-1-nitrobenzene is added and the mixture stirred for 1 1/2 hours. Water is added and the crude product filtered off. Recrystallization from methanol yields pure 2-amino-4-methylthio-1-nitrobenzene.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04072696 |
| 出典データセット | uspto-grants-1978_02 |
| ORD ID | ord-43643d142c7d4c63805eee68d7c23fa8 |
| 出典メモ | uspto-grants-1978_02 |