Methoxycarbonyl isothiocyanate → 1,2-Bis-(3-methoxycarbonyl-2-thioureido)-4-n-butylthiobenzene

HRID 616111ノート

反応式

HRID 616111 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH2:11][CH3:12])=[CH:4][C:3]=1[NH2:13].[CH3:14][O:15][C:16]([N:18]=[C:19]=[S:20])=[O:17]>CC(C)=O>[CH3:14][O:15][C:16]([NH:18][C:19](=[S:20])[NH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH2:11][CH3:12])=[CH:4][C:3]=1[NH:13][C:19]([NH:18][C:16]([O:15][CH3:14])=[O:17])=[S:20])=[O:17]

参加物

4

反応物 2

HCID 552246Methoxycarbonyl isothiocyanateHCID 203710591,2-Diamino-4-n-butylthiobenzene

生成物 1

HCID 203710011,2-Bis-(3-methoxycarbonyl-2-thioureido)-4-n-butylthiobenzene

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

1.5 G. of 1,2-diamino-4-n-butylthiobenzene in 30 ml. acetone is treated overnight with 4.5 g. methoxy carbonyl isothiocyanate at room temperature. The solution is concentrated, and the residue triturated with methanol and recrystallized from methanol, yielding 1,2-bis-(3-methoxycarbonyl-2-thioureido)-4-n-butylthiobenzene.

後処理

  1. customat room temperature
  2. concentrationThe solution is concentrated
  3. customthe residue triturated with methanol
  4. customrecrystallized from methanol

出典と根拠

ORDレコード
ord-1fcb6efa55084cf587e8dcbb4d3dc644
出典データセット
uspto-grants-1978_02
特許番号
US04072696

反応ノート

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