Methoxycarbonyl isothiocyanate → 4-Carbamoylthio-1-(3-methoxycarbonyl-2-thioureido)-2-nitrobenzene
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9](=[O:11])[NH2:10])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH3:15][O:16][C:17]([N:19]=[C:20]=[S:21])=[O:18]>CC(C)=O>[C:9]([S:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][C:20]([NH:19][C:17]([O:16][CH3:15])=[O:18])=[S:21])=[C:3]([N+:12]([O-:14])=[O:13])[CH:4]=1)(=[O:11])[NH2:10]参加物
4
実験手順
1 G. of 1-amino-4-carbamoylthio-2-nitrobenzene in 20 ml. acetone is treated with 3.0 g. methoxy carbonyl isothiocyanate at room temperature for several days. The solution is concentrated and the residue triturated with methanol to afford 4-carbamoylthio-1-(3-methoxycarbonyl-2-thioureido)-2-nitrobenzene.
後処理
- concentrationThe solution is concentrated
- customthe residue triturated with methanol
出典と根拠
- ORDレコード
- ord-04a64dede676417ab16f660662c95e2c
- 出典データセット
- uspto-grants-1978_02
- 特許番号
- US04072696
反応ノート
読み込み中…