7-Aminodeacetoxycephalosporanic acid → Cephalexin

HRID 616226

反応式

HRID 616226 の反応式
[CH3:1][C:2]1[CH2:11][S:10][C@@H:5]2[C@H:6]([NH2:9])[C:7](=[O:8])[N:4]2[C:3]=1[C:12]([OH:14])=[O:13].C[O:16][C:17]([C@H:19]([NH2:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=O.Cl>>[CH3:1][C:2]1[CH2:11][S:10][C@@H:5]2[C@H:6]([NH:9][C:17]([C@H:19]([NH2:26])[C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)=[O:16])[C:7](=[O:8])[N:4]2[C:3]=1[C:12]([OH:14])=[O:13]

参加物

3

反応物 2

HCID 334987-Aminodeacetoxycephalosporanic acidHCID 12247453D-Phenylglycine methyl ester hydrochloride

生成物 1

HCID 27447Cephalexin

実験手順

The wet mycelium so obtained is suspended in M/30-phosphate buffer (pH 6.0), containing 7-aminodeacetoxycephalosporanic acid and D-α-phenylglycine methyl ester hydrochloride (0.4 g), at 28° C for 24 hours. The amount of Cefalexin formed in the reaction mixture is 0.095 g when determined by microbiological assay.

後処理

  1. customThe wet mycelium so obtained

出典と根拠

ORDレコード
ord-a28de56108644757b01c0c05604cb9ff
出典データセット
uspto-grants-1978_02
特許番号
US04073687

関連ノート

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