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Ammonia → 2-(Amino(methylthio)methylene)malononitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | Methanethiol | HCID 878 | — |
| 反応物 | Acrylonitrile | HCID 7855 | — |
| 反応物 | 2-(Bis(methylsulfanyl)methylidene)propanedinitrile | HCID 99229 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-(Amino(methylthio)methylene)malononitrile | HCID 4409233 | — |
反応手順
Two liters of ethanol were saturated with ammonia gas at 15°. At ambient temperature, 278.3 g of 2-cyano-3,3-bis(methylthio)propenenitrile were added portionwise. A sodium hydroxide trap was used to trap the methyl mercaptan by-product. After complete addition of the propenenitrile the reaction mixture was cooled to approximately 10°. The solid which separated was collected by filtration and washed with cold ethanol to give, after drying, 206.3 g of white 3-amino-2-cyano-3-(methylthio)propenenitrile, m.p. 228°-230°. The nmr was consistent with the assigned structure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04075001 |
| 出典データセット | uspto-grants-1978_02 |
| ORD ID | ord-ff596e9f27bf4f31a60fdb7b1c4ade32 |
| 出典メモ | uspto-grants-1978_02 |