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HCID 20368146、化合物 → 1H-1,4-Benzodiazepine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | HCID 20368146 | HCID 20368146 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 溶媒 | Acetyl chloride | HCID 6367 | — |
| 生成物 | 1H-1,4-Benzodiazepine | HCID 148431 | — |
反応手順
In the manner given in Example 1, a solution of 8-fluoro-1-methyl-6-(o-fluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in dimethylformamide, N,N,N',N'-tetrapropyldiaminomethane and acetyl chloride (in 0.5 molar excess compared to the N,N,N',N'-tetrapropyldiaminomethane) are reacted together to give 8-fluoro-1[2-(dipropylamino)ethyl]-6-(o-fluorophenyl)-4H-s-triazolo[4,3-a][1,4-benzodiazepine
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04075221 |
| 出典データセット | uspto-grants-1978_02 |
| ORD ID | ord-e375e263f104480eb2604e29d92efb05 |
| 出典メモ | uspto-grants-1978_02 |