関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phosgene | HCID 6371 | — |
| 反応物 | 10-fluoro-5H-dibenz[b,f]azepine | HCID 20366408 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 10-fluoro-5H-dibenz[b,f]azepine-5-carbonyl chloride | HCID 20366410 | — |
反応手順
A mixture of 2.3 g of 10-fluoro-5H-dibenz[b,f]azepine and 30 ml of toluene saturated with phosgene is stirred for 2 days at 25° C. Excess phosgene is then expelled with nitrogen and the reaction mixture is concentrated by rotary evaporation to yield crude 10-fluoro-5H-dibenz[b,f]azepine-5-carbonyl chloride as residue.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04076812 |
|---|
| 出典データセット | uspto-grants-1978_02 |
|---|
| ORD ID | ord-84342a3214e94d54b38ef2410a598ec3 |
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| 出典メモ | uspto-grants-1978_02 |
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