Dichloromethane → HCID 19390523、化合物
反応式
[CH2:1]([O:3][C:4]([NH:6][NH:7][CH:8]([CH3:10])[CH3:9])=[O:5])[CH3:2].C(=O)(O)[O-].[Na+].C(Cl)Cl.[N:19]#[C:20]Cl>O>[CH2:1]([O:3][C:4]([NH:6][N:7]([CH:8]([CH3:10])[CH3:9])[C:20]#[N:19])=[O:5])[CH3:2]参加物
6
実験手順
73.0 g of 2-isopropylhydrazinecarboxylic acid ethyl ester and 42.0 g of sodium bicarbonate are stirred into 200 ml of methylene chloride and 400 ml of water. There is then introduced at room temperature in the course of 20 minutes, with continuous stirring, 30.8 g of gaseous cyanogen chloride. After an hour's stirring, the methylene chloride base is separated, dried over sodium sulphate and the solvent is distilled off in vacuo. There is obtained as residue 75.0 g (87.5% of theory) of 2-isopropyl-2-cyanohydrazinecarboxylic acid ethyl ester as colourless oil.
後処理
- customthe methylene chloride base is separated
- dry with materialdried over sodium sulphate
- distillationthe solvent is distilled off in vacuo
出典と根拠
- ORDレコード
- ord-9b2990f0431544318ddbd48fceac40cf
- 出典データセット
- uspto-grants-1978_02
- 特許番号
- US04076938
反応ノート
読み込み中…