関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Isopropyl isocyanate | HCID 61277 | — |
| 反応物 | N-[[(3,5-dichlorophenyl)amino]carbonyl]glycine | HCID 595293 | — |
| 溶媒 | Chlorobenzene | HCID 7964 | — |
| 生成物 | Iprodione | HCID 37517 | 100.6% |
反応手順
101 g of triethylamine are added to a suspension of 263 g of 2-[3-(3,5-dichlorophenyl)-ureido]-acetic acid in 2,000 cm3 of chlorobenzene and 300 g of isopropyl isocyanate, which has been heated to 50° C, and the mixture is stirred for 4 hours at 80°-90°. After cooling, the reaction mixture is stirred for 30 minutes with 500 cm3 of a 7% strength (weight/volume) aqueous solution of hydrochloric acid. The organic solution is decanted, dried and concentrated under reduced pressure. 332 g of 1-isopropylcarbamoyl-3-(3,5-dichlorophenyl)-hydantoin melting at 130° C are thus obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04076941 |
|---|
| 出典データセット | uspto-grants-1978_02 |
|---|
| ORD ID | ord-9783e2e49edf49a3a030f93600e2b706 |
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| 出典メモ | uspto-grants-1978_02 |
|---|
