beta-Aminobeta-ethoxyacrylic acid ethyl ester → 3-Amino-1-(3-fluorobenzyl)-pyrazol-5-one
反応式
C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.[F:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[CH2:16][NH:17][NH2:18]>C(O)C>[NH2:10][C:6]1[NH:18][N:17]([CH2:16][C:15]2[CH:19]=[CH:20][CH:21]=[C:13]([F:12])[CH:14]=2)[C:4](=[O:3])[CH:5]=1参加物
4
実験手順
17.5 g of β-amino-β-ethoxyacrylic acid ethyl ester and 13 g of 3-fluorobenzylhydrazine, on stirring for 5 hours in ethanol at 60° and working up as described in Example 1, yield 11.3 g, corresponding to 55% of theory, of the compound identified above as colorless crystals of melting point 129°.
出典と根拠
- ORDレコード
- ord-cb77c800d37741b9ad8728bc09830f55
- 出典データセット
- uspto-grants-1978_02
- 特許番号
- US04076943
反応ノート
読み込み中…