N-(2-Chloroethyl)urea → 1-(2-(3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yloxy)ethyl)urea

HRID 61711

反応式

HRID 61711 の反応式
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17](=[O:18])[C:16]3[C:15]4[C:10](=[CH:11][C:12]([C:19]#[N:20])=[CH:13][CH:14]=4)[NH:9][C:8]=3[C:7]([CH3:22])([CH3:21])[C:6]=2[CH:23]=1.Cl[CH2:25][CH2:26][NH:27][C:28]([NH2:30])=[O:29]>>[C:19]([C:12]1[CH:11]=[C:10]2[C:15]([C:16]3[C:17](=[O:18])[C:5]4[CH:4]=[CH:3][C:2]([O:1][CH2:25][CH2:26][NH:27][C:28]([NH2:30])=[O:29])=[CH:23][C:6]=4[C:7]([CH3:21])([CH3:22])[C:8]=3[NH:9]2)=[CH:14][CH:13]=1)#[N:20]

参加物

3

反応物 2

HCID 240817N-(2-Chloroethyl)ureaHCID 668338618-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

生成物 1

HCID 545828501-(2-(3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yloxy)ethyl)urea

実験手順

Under the same conditions as the method for synthesizing Compound A7-17, the title compound was prepared from Compound A6 and 2-chloroethylurea.

後処理

  1. customUnder the same conditions as the method for synthesizing Compound A7-17

出典と根拠

ORDレコード
ord-88019440c1084d54b4fd63b53b733dda
出典データセット
uspto-grants-2016_09
特許番号
US09440922B2

関連ノート

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