関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-Bromooctane | HCID 8140 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 4'-Hydroxy-4-biphenylcarboxylic acid | HCID 301556 | — |
| 生成物 | 4'-(Octyloxy)-[1,1'-biphenyl]-4-carboxylic acid | HCID 2802556 | — |
反応手順
n-Octyl bromide (0.102 mol) is added to a solution of 4-(4-hydroxyphenyl)benzoic acid (0.102 mol) and 2.5 N sodium hydroxide (0.102 mol) and the mixture stirred at 70° C. for a period of 18 hours. The reaction mixture is allowed to cool and then acidified to pH 3 and partitioned between ethyl acetate and water. The organic phase is washed with water and brine and the solvent then removed to obtain the 4'-n-octyloxy-[1,1'-biphenyl]-4-ylcarboxylic acid, C21H23O3, M.W. 326.4
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05948753 |
|---|
| 出典データセット | uspto-grants-1999_09 |
|---|
| ORD ID | ord-1b3a60408c6b4b91a7c7f2cdc4ed6e53 |
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| 出典メモ | uspto-grants-1999_09 |
|---|
