関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Aniline | HCID 6115 | — |
| 反応物 | Hexane | HCID 8058 | — |
| 反応物 | 1-Bromoadamantane | HCID 79106 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | N-phenyladamantan-1-amine | HCID 303939 | — |
反応手順
Under a nitrogen (N2) atmosphere was combined 10.0 g (46.5 mmol) of 1-bromoadamantane and 20 ml of aniline. The reaction was stirred for 20 hours at 200° C., and then cooled and fractionated on silica gel using 6:1 hexane:ethyl acetate (EtOAc) to afford, after concentration in vacuo and refractionation using toluene, 5.65 g (54%) of N-1-adamantylaniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05948781 |
|---|
| 出典データセット | uspto-grants-1999_09 |
|---|
| ORD ID | ord-b55a2f58a31a42d9b38ecbebfa45ab7a |
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| 出典メモ | uspto-grants-1999_09 |
|---|
