Diethyl ethylmalonate → 2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

HRID 617601ノート

反応式

HRID 617601 の反応式
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=[O:23])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH:15]([OH:23])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

参加物

3

反応物 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772、化合物

生成物 1

HCID 226187962-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

実験手順

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is treated in the same manners as working example 79 and then working example 80 to give the subject compound.

後処理

  1. customobtained
  2. additionis treated in the same manners
  3. customto give the subject compound

出典と根拠

ORDレコード
ord-46539a9f00db4d518e5ff82697b519a2
出典データセット
uspto-grants-1999_09
特許番号
US05948820

反応ノート

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