2-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol → 2-Amino-2-(1,2-dihydroxyoctadecyl)-1,3-propanediol

HRID 617873ノート

反応式

HRID 617873 の反応式
[NH2:1][C:2]([CH:7]([OH:26])[CH:8]([OH:25])[CH2:9][CH:10]=[CH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([CH2:5][OH:6])[CH2:3][OH:4]>CO.[C].[Pd]>[NH2:1][C:2]([CH:7]([OH:26])[CH:8]([OH:25])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([CH2:3][OH:4])[CH2:5][OH:6]

参加物

4

反応物 1

HCID 538638012-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol

生成物 1

HCID 218493532-Amino-2-(1,2-dihydroxyoctadecyl)-1,3-propanediol収率 50.2%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 887Methanol溶媒

実験手順

2-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol (68.0 mg) was dissolved in 14 ml of methanol and 6.8 mg of 5% palladium-carbon was added thereto. The catalytic reduction was conducted at ordinary temperature and at atmospheric pressure day and night. After the reaction, the catalyst was filtered off and the filtrate was concentrated under reduced pressure to give 34.3 mg of the subject compound.

後処理

  1. customAfter the reaction
  2. filtrationthe catalyst was filtered off
  3. concentrationthe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-dda39b44ffd84448bec54c3cc1259b31
出典データセット
uspto-grants-1999_09
特許番号
US05952316

反応ノート

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