関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Imidazole | HCID 795 | — |
| 反応物 | 5-Chloro-2-nitrobenzonitrile | HCID 100506 | — |
| 溶媒 | Dimethylacetamide | HCID 31374 | — |
| 生成物 | 5-(1-Imidazolyl)-2-nitrobenzonitrile | HCID 21847820 | 107.8% |
反応手順
A mixture of 5-chloro-2-nitrobenzonitrile (20.0 g) and imidazole (22.3 g) in DMA (150 ml) was heated at 140° C. for 6 hours. The mixture was evaporated and the residue was triturated with water to give 5-(1-imidazolyl)-2-nitrobenzonitrile (25.3 g); NMR Spectrum: (CD3SOCD3) 7.20 (d, 1H), 8.05 (t, 1H), 8.28 (m, 1H), 8.62 (m, 2H), 8.51 (d, 1H);
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05955464 |
|---|
| 出典データセット | uspto-grants-1999_09 |
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| ORD ID | ord-d929b6519f5a4617a4c00bf24f28fa1a |
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| 出典メモ | uspto-grants-1999_09 |
|---|
