Serinol → HCID 21844896、化合物
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([NH:14][C:15]([C:17]2[CH:22]=[C:21]([C:23](OC)=[O:24])[CH:20]=[C:19]([N+:27]([O-:29])=[O:28])[CH:18]=2)=[O:16])[CH:7]=[C:8]([C:10](OC)=[O:11])[CH:9]=1)([O-:3])=[O:2].[NH2:30][CH:31]([CH2:34][OH:35])[CH2:32][OH:33]>>[N+:1]([C:4]1[CH:5]=[C:6]([NH:14][C:15]([C:17]2[CH:22]=[C:21]([C:23]([NH:30][CH:31]([CH2:34][OH:35])[CH2:32][OH:33])=[O:24])[CH:20]=[C:19]([N+:27]([O-:29])=[O:28])[CH:18]=2)=[O:16])[CH:7]=[C:8]([C:10]([NH:30][CH:31]([CH2:34][OH:35])[CH2:32][OH:33])=[O:11])[CH:9]=1)([O-:3])=[O:2]参加物
3
反応条件
- 温度
- 95 °C
実験手順
3-Nitro-5-methoxycarbonylphenylaminocarbonyl-(3'-nitro-5'-methoxycarbonylbenzene) (0.40 g, 1.0 mmol) and serinol (0.23 g, 2.5 mmol) were mixed and heated to 95° C. After 30 min, the pressure was reduced to 200 mm Hg and heating was continued for 3 h. The reaction mixture was purified by preparative HPLC. Yield: 0.27 g (52%).
後処理
- temperatureheating
- waitwas continued for 3 h
- customThe reaction mixture was purified by preparative HPLC