Benzonitrile, 4-chloro-3-nitro- → 6-Cyano-2-[1-(6-methoxy-pyridin-2-yl)-1-methyl-ethyl]-1H-indole-3-carboxylic acid tert-butyl ester
反応式
[C:1]([O:5][C:6](=[O:21])[CH2:7][C:8](=O)[C:9]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[N:13]=1)([CH3:11])[CH3:10])([CH3:4])([CH3:3])[CH3:2].Cl[C:23]1[CH:30]=[CH:29][C:26]([C:27]#[N:28])=[CH:25][C:24]=1[N+:31]([O-])=O>>[C:1]([O:5][C:6]([C:7]1[C:23]2[C:24](=[CH:25][C:26]([C:27]#[N:28])=[CH:29][CH:30]=2)[NH:31][C:8]=1[C:9]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[N:13]=1)([CH3:11])[CH3:10])=[O:21])([CH3:4])([CH3:3])[CH3:2]参加物
3
実験手順
According to the method that is used for the preparation of Compound PR5-1, the title compound was synthesized from 4-(6-methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester and 4-chloro-3-nitrobenzonitrile
後処理
- customis used for the preparation of Compound PR5-1