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Triethylamine → N-(2-mesitylenesulfonyl)-p-styrenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 2-Mesitylenesulfonyl chloride | HCID 13046 | — |
| 反応物 | 4-(Sulfonamido)styrene | HCID 280935 | — |
| 触媒 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | N-(2-mesitylenesulfonyl)-p-styrenesulfonamide | HCID 21845203 | 64.7% |
反応手順
Using 55.0 g (0.3 mol) of p-styrenesulfonamide, 3.7 g (0.03 mol) of 4-(N,N-dimethylamino)pyridine, 82.0 g (0.81 mol) of triethylamine, 91.8 g (0.42 mol) of 2-mesitylenesulfonyl chloride, and 500 ml of acetonitrile, reaction was conducted in the same manner as in Synthesis Example 1. As a result, 70.9 g of N-(2-mesitylenesulfonyl) -p-styrenesulfonamide was obtained (yield, 64.7%; light-yellow crystals; m.p., 146.5-147° C.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05958646 |
| 出典データセット | uspto-grants-1999_09 |
| ORD ID | ord-d9011c8d0ac64ae9b12a0f6d68f23ef9 |
| 出典メモ | uspto-grants-1999_09 |