Benzonitrile, 4-chloro-3-nitro- → 6-Cyano-2-[1-(6-methoxy-pyridin-2-yl)-1-methyl-ethyl]-benzofuran-3-carboxylic acid tert-butyl ester

HRID 61897

反応式

HRID 61897 の反応式
[C:1]([O:5][C:6](=[O:21])[CH2:7][C:8](=[O:20])[C:9]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[N:13]=1)([CH3:11])[CH3:10])([CH3:4])([CH3:3])[CH3:2].Cl[C:23]1[CH:30]=[CH:29][C:26]([C:27]#[N:28])=[CH:25][C:24]=1[N+]([O-])=O>>[C:1]([O:5][C:6]([C:7]1[C:23]2[CH:24]=[CH:25][C:26]([C:27]#[N:28])=[CH:29][C:30]=2[O:20][C:8]=1[C:9]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[N:13]=1)([CH3:11])[CH3:10])=[O:21])([CH3:2])([CH3:3])[CH3:4]

参加物

3

反応物 2

HCID 13655Benzonitrile, 4-chloro-3-nitro-HCID 668345394-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester

生成物 1

HCID 668344066-Cyano-2-[1-(6-methoxy-pyridin-2-yl)-1-methyl-ethyl]-benzofuran-3-carboxylic acid tert-butyl ester

実験手順

According to the method that is used for the preparation of Compound FR1, the title compound was synthesized from 4-(6-methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester and 4-chloro-3-nitrobenzonitrile.

出典と根拠

ORDレコード
ord-7e7ff614c63f474d92f2da8d138cf8ab
出典データセット
uspto-grants-2016_09
特許番号
US09440922B2

関連ノート

読み込み中…