関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | N-Hydroxyphthalimide | HCID 10665 | — |
| 反応物 | 1,3-Dimethyladamantane | HCID 12800 | — |
| 生成物 | 1,3-Dimethyladamantane | HCID 12800 | — |
| 生成物 | 3,5-Dimethyl-1-adamantanol | HCID 265793 | 39% |
| 生成物 | 5,7-Dimethyladamantane-1,3-diol | HCID 580605 | 58% |
反応手順
A mixture of 1.64 grams (10 millimoles) of 1,3-dimethyladamantane, 0.13 gram (0.8 millimole) of N-hydroxyphthalimide, 0.015 gram (0.06 millimole) of Co(AA)2 and 10 milliliters of acetic acid was stirred under oxygen atmosphere at a temperature of 70° C. for six hours. As a result, with a transformation rate for 1,3-dimethyladamantane of 99%, 1-hydroxy-3,5-dimethyladamantane (yield 39%), and 1,3-dihydroxy-5,7-dimethyladamantane (yield 58%) were obtained. The selectivity for the alcohols was 97%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05958821 |
|---|
| 出典データセット | uspto-grants-1999_09 |
|---|
| ORD ID | ord-2a851c4fea1843b5989ebbc860497b17 |
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| 出典メモ | uspto-grants-1999_09 |
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