関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-(3-(Benzyloxy)phenyl)-2-bromoethanone | HCID 88031 | — |
| 反応物 | Thiourea | HCID 2723790 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4-[3-(Benzyloxy)phenyl]-1,3-thiazol-2-amine hydrobromide | HCID 16495478 | — |
反応手順
A solution of 22.5 g of 2-bromo-1-(3-benzyloxy-phenyl)-ethanone in 150 ml of methanol was treated at room temperature with 7.8 g of thiourea and boiled for 1 hour. 16.1 g of 4-(3-benzyloxy-phenyl)-thiazol-2-ylamine hydrobromide separated as colorless crystals upon cooling to 0° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05958910 |
|---|
| 出典データセット | uspto-grants-1999_09 |
|---|
| ORD ID | ord-d890b3c21f4a41788064f13ffdf142bb |
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| 出典メモ | uspto-grants-1999_09 |
|---|
