Aluminium lithium hydride → HCID 21995277、化合物
反応式
OCC1C=CC(C2C=CN=C(NC3C=C(OC)C(OC)=C(OC)C=3)N=2)=CC=1.C([O:35][C:36]([CH2:38][C:39]1[CH:44]=[CH:43][C:42]([NH:45][C:46]2[CH:51]=[CH:50][N:49]=[C:48]([NH:52][C:53]3[CH:58]=[C:57]([O:59][CH3:60])[C:56]([O:61][CH3:62])=[C:55]([O:63][CH3:64])[CH:54]=3)[N:47]=2)=[CH:41][CH:40]=1)=O)C1C=CC=CC=1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[OH:35][CH2:36][CH2:38][C:39]1[CH:44]=[CH:43][C:42]([NH:45][C:46]2[CH:51]=[CH:50][N:49]=[C:48]([NH:52][C:53]3[CH:54]=[C:55]([O:63][CH3:64])[C:56]([O:61][CH3:62])=[C:57]([O:59][CH3:60])[CH:58]=3)[N:47]=2)=[CH:41][CH:40]=1参加物
4
実験手順
In a manner analogous to the preparation of the compound of Example 62 (267 mg, 0.5 mmol) from the compound of Example 106 and LiAlH4 (40 mg, 1.1 mmol) to give the title compound (108 mg) as a light pink solid m.p. 172°. MS m/z 397 (M+H)+.
出典と根拠
- ORDレコード
- ord-f8a68f7265e941548c246520ccb8453d