Methyl 4-[2-benzenesulphonamidoindan-5-yl]-4-oxobutyrate → HCID 14071508、化合物

HRID 620196ノート

反応式

HRID 620196 の反応式
[C:1]1([S:7]([NH:10][CH:11]2[CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([C:20](=[O:27])[CH2:21][CH2:22][C:23]([O:25]C)=[O:24])[CH:17]=3)[CH2:12]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(O)C>[C:1]1([S:7]([NH:10][CH:11]2[CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([C:20](=[O:27])[CH2:21][CH2:22][C:23]([OH:25])=[O:24])[CH:17]=3)[CH2:12]2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

3

反応物 1

HCID 14071507Methyl 4-[2-benzenesulphonamidoindan-5-yl]-4-oxobutyrate

生成物 1

HCID 14071508HCID 14071508、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

2.7 ml of 15N sodium hydroxide solution are added to 8.3 g (21.4 mmol) of methyl 4-[2-benzenesulphonamidoindan-5-yl]-4-oxobutyrate in 20 ml of ethanol and the mixture is boiled for 2 hours. The mixture is evaporated in vacuo, the residue is taken up in water, and the reaction product is precipitated with hydrochloric acid. It is crystallised from ethyl acetate/diisopropyl ether.

後処理

  1. customThe mixture is evaporated in vacuo
  2. customthe reaction product is precipitated with hydrochloric acid
  3. customIt is crystallised from ethyl acetate/diisopropyl ether

出典と根拠

ORDレコード
ord-4e477668029a4d19b09425406df9fe92
出典データセット
uspto-grants-1989_04
特許番号
US04820705

反応ノート

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