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1-Pyrenecarboxaldehyde → 3-Methoxy-2-methyl-2-((7-pyrenylmethyl)amino)-1-propanol methanesulfonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Pyrenecarboxaldehyde | HCID 232848 | — |
| 反応物 | 2-Amino-3-methoxy-2-methylpropan-1-ol | HCID 13375415 | — |
| 反応物 | (+-)(2R*,3S*)-2-((1-Pyrenylmethyl)amino)-2-methyl-1,3-butanediol hydrochloride | HCID 86742932 | — |
| 反応物 | 3-Methoxy-2-methyl-2-((1-pyrenylmethyl)amino)-1-propanol methanesulfonate | HCID 88645326 | — |
| 生成物 | 3-Methoxy-2-methyl-2-((7-pyrenylmethyl)amino)-1-propanol methanesulfonate | HCID 53638411 | — |
反応手順
Using the reductive amination procedure outlined in 20G, pyrene-1-carbaldehyde (Aldrich) and 2-amino-3-methoxy-2-methyl-1-propanol (22C) gave after workup using the procedure outlined in 1B 3-methoxy-2-methyl-2-((1-pyrenylmethyl)amino)-1-propanol methanesulfonate.1/3H2O mp 158°-160°, (EtOH/Et2O), (C, H, N, S).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04820873 |
| 出典データセット | uspto-grants-1989_04 |
| ORD ID | ord-a8dd000b0bbd490a90074a43bb0df29b |
| 出典メモ | uspto-grants-1989_04 |