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2-(Bis(methylsulfanyl)methylidene)propanedinitrile → 5-Amino-4-cyano-3-methylthio-1-(3-trifluoromethylbenzyl)-pyrazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Bis(methylsulfanyl)methylidene)propanedinitrile | HCID 99229 | — |
| 反応物 | ((3-(Trifluoromethyl)phenyl)methyl)hydrazine | HCID 599698 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 5-Amino-4-cyano-3-methylthio-1-(3-trifluoromethylbenzyl)-pyrazole | HCID 14071022 | 80% |
反応手順
8.5 g (0.05 mol) of 1,1-dicyano-2,2-bis(methylthio)-ethylene and 9.5 g (0.06 mol) of 3-trifluoromethylbenzyl-hydrazine (compare DE-OS (German Published Specification) No. 2,230,675) are stirred in 100 ml of ethanol at 20° C. for 15 hours. For working up, the solvent is removed in vacuo and the residue is triturated with petroleum ether. Filtration with suction gives 12.4 g (80% of theory) of 5-amino-4-cyano-3-methylthio-1-(3-trifluoromethylbenzyl)-pyrazole of melting point 142° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04822810 |
| 出典データセット | uspto-grants-1989_04 |
| ORD ID | ord-de997f3e971c4dd9aecbe41bad4dd182 |
| 出典メモ | uspto-grants-1989_04 |