Hydroxylamine → HCID 21293763、化合物

反応式

C([O:4][N:5]([CH:9]([C:11]1[CH:12]=[CH:13][C:14]2[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=3[O:16][C:15]=2[CH:23]=1)[CH3:10])[C:6](=[O:8])[CH3:7])(=O)C.C(OC(=O)C)(=O)C.NO.C(N(CC)CC)C>C(Cl)Cl>[OH:4][N:5]([CH:9]([C:11]1[CH:12]=[CH:13][C:14]2[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=3[O:16][C:15]=2[CH:23]=1)[CH3:10])[C:6](=[O:8])[CH3:7]

参加物

実験手順

N-acetoxy-N-(1-dibenzofur-3-ylethyl) acetamide. Acetic anhydride (9.0 mL) was added to a solution of the crude hydroxylamine, prepared as in step c, and triethyl amine (12.4 mL) in methylene chloride (50 mL). The reaction was stirred overnight, then washed with cold water and 3 N HCl. The methylene chloride layer was dried (Na2SO4) and concentrated to give a yellowish oil. This residue was chromatographed on 100 g of silica gel, eluting with 20% ethyl acetate in hexanes to give the desired product.