Toluene → 1-tert-Butyl-2,5-dichloro-4-methylbenzene

HRID 620958ノート

反応式

HRID 620958 の反応式
[Cl-:1].[Al+3].[Cl-:3].[Cl-].[C:5]1([CH3:11])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>>[Cl:1][C:6]1[CH:7]=[C:8]([C:5]([CH3:11])([CH3:10])[CH3:6])[C:9]([Cl:3])=[CH:10][C:5]=1[CH3:11]

参加物

3

反応物 2

HCID 1140TolueneHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 144188301-tert-Butyl-2,5-dichloro-4-methylbenzene収率 270.8%

実験手順

After adding a large excess of 2000 g of toluene and 64 g (0.48 mol) of anhydrous aluminum chloride, as a catalyst, to 284 g (1.3 mol) of 2,5-dichloro-4-t-butyltoluene obtained as stated above, the mixture was brought into reaction for 5 hours at room temperature under a vigorous agitation thereof.

出典と根拠

ORDレコード
ord-7d240177babf4591935d6a2ff34f315a
出典データセット
uspto-grants-1989_04
特許番号
US04822928

反応ノート

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