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(1-Chloroethyl)benzene → 1-(3-Vinylphenyl)-1-phenylethane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (1-Chloroethyl)benzene | HCID 12648 | — |
| 反応物 | HCID 178436337 | HCID 178436337 | — |
| 生成物 | 1-(3-Vinylphenyl)-1-phenylethane | HCID 14750258 | — |
反応手順
(1-Chloroethyl)benzene (formula VI) is subjected to coupling reaction with a Grignard reagent of 3-vinylphenylmagnesium bromide (formula VII) in the presence of a catalyst of nickel chloride (II)-diphosphine complex, to obtain 1-(3-vinylphenyl)-1-phenylethane. The reaction is carried out in a nitrogen atmosphere under atmospheric pressure at a temperature of 0° to 80° C. The ratio of (VI)/(VII) may be in the range of about 1.0 to 1.5. ##STR9##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04822934 |
| 出典データセット | uspto-grants-1989_04 |
| ORD ID | ord-c751cc797d1948abb698a6f491abf4ef |
| 出典メモ | uspto-grants-1989_04 |