化工社化工社 化学情報印刷レポート · 研究参考用
Triethyl orthoacetate → 2-Methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethyl orthoacetate | HCID 66221 | — |
| 反応物 | 3-Nitrobenzohydrazide | HCID 3291498 | — |
| 生成物 | 2-Methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole | HCID 2806331 | — |
反応手順
3-Nitrobenzoic acid, hydrazide, 24.5 g, (Chemical Abstracts, Vol. 102, 148507r (1983)) and 1,1,1-triethoxyethane are refluxed overnight. The mixture is cooled, filtered, and washed with hexane to give 21.9 g of 2-methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole after recrystallization from 2-propanol; mp 154°-156° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04824843 |
| 出典データセット | uspto-grants-1989_04 |
| ORD ID | ord-98704e72f22c4bcb92d71e2e7f36b26c |
| 出典メモ | uspto-grants-1989_04 |