化工社化工社 化学情報印刷レポート · 研究参考用
Iodine → 2-Amino-4-(4-methoxyphenyl)thiazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodine | HCID 807 | — |
| 反応物 | 4'-Methoxyacetophenone | HCID 7476 | — |
| 反応物 | Thiourea | HCID 2723790 | — |
| 生成物 | 2-Amino-4-(4-methoxyphenyl)thiazole | HCID 159644 | 91.7% |
反応手順
33.5 g of thiourea are added to 30 g of 4-methoxyacetophenone, 56 g of iodine are added and the mixture is kept at 100° C. for 5 hours. The reaction mixture is discharged onto water, powdered, washed several times with ether then with ammonia solution and finally with water, and dried. 37.8 g of 4-(4-methoxyphenyl)-thiazol-2-yl-amine of melting point 194°-205° C. are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04769062 |
| 出典データセット | uspto-grants-1988_09 |
| ORD ID | ord-09dba717f1474456a3f92a8f3ab1376d |
| 出典メモ | uspto-grants-1988_09 |