2,3-Quinolinedicarboxylic acidtrihydrate → Furo[3,4-b]quinoline-1,3-dione

HRID 622165

反応式

HRID 622165 の反応式
O.O.O.[N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[C:6]([C:14]([OH:16])=O)[C:5]=1[C:17]([OH:19])=[O:18]>C(OC(=O)C)(=O)C>[N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[C:6]2[C:14]([O:19][C:17](=[O:18])[C:5]=12)=[O:16]

参加物

3

反応物 1

HCID 155583142,3-Quinolinedicarboxylic acidtrihydrate

生成物 1

HCID 4325463Furo[3,4-b]quinoline-1,3-dione

試薬・触媒・溶媒 1

HCID 7918Acetic Anhydride溶媒

反応条件

温度
85 °C

実験手順

A mixture of 2,3-quinolinedicarboxylic acidtrihydrate (0.141 mol) in acetic anhydride (125 mL) is heated at 85° C. for 1/2 hour and then at 100° C. for 1 hour. The reaction mixture is then cooled to room temperature, filtered and the solids washed with ethyl ether to afford the desired 2,3-quinolinedicarboxylic anhydride, mp 225°-228° C.

後処理

  1. temperatureThe reaction mixture is then cooled to room temperature
  2. filtrationfiltered
  3. washthe solids washed with ethyl ether

出典と根拠

ORDレコード
ord-179810233d824550a3d5f22bdfb74c0b
出典データセット
uspto-grants-1988_09
特許番号
US04769462

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