Ethanol → HCID 21294041、化合物

HRID 622245ノート

反応式

HRID 622245 の反応式
[C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[C:6]([CH2:18][CH2:19][CH3:20])[C:5]=1[OH:21])(=[O:3])[CH3:2].S(=O)(=O)(O)O.[CH2:27](O)[CH3:28]>>[C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([O:15][CH2:27][CH3:28])=[O:14])=[C:6]([CH2:18][CH2:19][CH3:20])[C:5]=1[OH:21])(=[O:3])[CH3:2]

参加物

4

反応物 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 13753872HCID 13753872、化合物

生成物 1

HCID 21294041HCID 21294041、化合物

実験手順

Eleven grams of 5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentanoic acid were dissolved in 200 ml. of absolute ethanol. With stirring, 1 ml. of sulfuric acid was added and the reaction was stirred overnight. The solvent was evaporated in vacuo and the residue partitioned between ethyl acetate and dilute potassium carbonate solution. The ethyl acetate was separated, dried, and evaporated to give 9.9 g. of the title product, M+ =322.

後処理

  1. stirringthe reaction was stirred overnight
  2. customThe solvent was evaporated in vacuo
  3. customthe residue partitioned between ethyl acetate and dilute potassium carbonate solution
  4. customThe ethyl acetate was separated
  5. customdried
  6. customevaporated
  7. customto give 9.9 g

出典と根拠

ORDレコード
ord-dd06da591652446e9be57de52ed9e061
出典データセット
uspto-grants-1988_09
特許番号
US04769482

反応ノート

読み込み中…