化工社化工社 化学情報印刷レポート · 研究参考用
2-Trifluoromethylbenzenesulphonyl chloride → 1-(3-Chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-4-[[2-(trifluoromethyl)phenyl]sulfonyl]piperazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Trifluoromethylbenzenesulphonyl chloride | HCID 136616 | — |
| 反応物 | 1,4-Naphthalenedione, 2-chloro-3-(1-piperazinyl)- | HCID 699794 | — |
| 生成物 | 1-(3-Chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-4-[[2-(trifluoromethyl)phenyl]sulfonyl]piperazine | HCID 13934779 | — |
反応手順
A 1.5 g portion of 3-chloro-2-piperazinyl-1,4-naphthoquinone and 1.26 g of 2-trifluoromethylbenzenesulfonyl chloride were reacted as described in Example 56, giving 1.53 g of the desired product, mp 122-124°C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04771061 |
| 出典データセット | uspto-grants-1988_09 |
| ORD ID | ord-f42c658cf5834439a2d7400e43606b0b |
| 出典メモ | uspto-grants-1988_09 |