Hydrochloric Acid → 3-Methoxyiminopyrrolidine hydrochloride
反応式
[ClH:1].C(OC([N:9]1[CH2:13][CH2:12][C:11](=[N:14][O:15][CH3:16])[CH2:10]1)=O)(C)(C)C.CCOCC>C(OCC)(=O)C>[ClH:1].[CH3:16][O:15][N:14]=[C:11]1[CH2:12][CH2:13][NH:9][CH2:10]1参加物
5
反応条件
- 温度
- 40 °C
実験手順
7 ml of a 3M hydrogen chloride solution in ethyl acetate was added to 2.3 g of ice-cooled 1-(t-butoxycarbonyl)-3-methoxyiminopyrrolidine, and the mixture was stirred at about 40° C. for one hour. After completion of the reaction, the solvent was stripped off from the reaction mixture and ether was added to the residue. The crystals which formed were collected by filtration and washed with ether, giving 1.5 g of the title compound.
後処理
- customAfter completion of the reaction
- additionwas added to the residue
- customThe crystals which formed
- filtrationwere collected by filtration
- washwashed with ether
出典と根拠
- ORDレコード
- ord-717408610b5640e58a55825510da26e4
- 出典データセット
- uspto-grants-1988_09
- 特許番号
- US04771046
反応ノート
読み込み中…