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N,N-Dimethylmethanesulphonamide → 1-(4-fluoro-2-methylaminophenyl)-2-(N,N-dimethylsulphamoyl)ethanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N,N-Dimethylmethanesulphonamide | HCID 70191 | — |
| 反応物 | Methyl 4-fluoro-2-(methylamino)benzoate | HCID 13474393 | — |
| 反応物 | Butyllithium | HCID 178418339 | — |
| 生成物 | 1-(4-fluoro-2-methylaminophenyl)-2-(N,N-dimethylsulphamoyl)ethanone | HCID 21291488 | — |
反応手順
In a similar manner to that described in Example 12(a), N,N-dimethylmethanesulphonamide was reacted with n-butyl lithium and the product reacted with methyl 4-fluoro-2-methylaminobenzoate to give the novel compound 1-(4-fluoro-2-methylaminophenyl)-2-(N,N-dimethylsulphamoyl)ethanone, m.p. 120°-124°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04772614 |
| 出典データセット | uspto-grants-1988_09 |
| ORD ID | ord-c24a0e6d7e42499c8d2fc5ebb355d326 |
| 出典メモ | uspto-grants-1988_09 |