1,4-Dimethylpiperazine → N-alpha-chloroethoxycarbonyl N'-methyl piperazine
反応式
[CH3:1][N:2]1[CH2:7][CH2:6][N:5](C)[CH2:4][CH2:3]1.Cl[C:10]([O:12][CH:13]([Cl:15])[CH3:14])=[O:11]>>[Cl:15][CH:13]([O:12][C:10]([N:5]1[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]1)=[O:11])[CH3:14]参加物
3
実験手順
In a similar manner, N,N'-di-methylpiperazine is reacted with α-chloroethyl chloroformate (ACE-Cl) to give the intermediate N-α-chloroethoxycarbonyl N'-methyl piperazine, which is then dehydrohalogenated as in Example 21b to give N-(vinyloxycarbonyl)N'-methylpiperazine.
出典と根拠
- ORDレコード
- ord-fe6304217b9245949ae64174996e8177
- 出典データセット
- uspto-grants-1988_09
- 特許番号
- US04772695
反応ノート
読み込み中…