2-Thiophenecarbonyl chloride → Anthrimide

HRID 622839

反応式

HRID 622839 の反応式
[CH:1]1[CH:6]=[C:5]2[C:7]([C:9]3[C:14]([C:15](=[O:16])[C:4]2=[CH:3][CH:2]=1)=[C:13]([NH:17][C:18]1[CH:23]=[CH:22][C:21](N)=[C:20]2[C:25]([C:27]4[C:32]([C:33](=[O:34])[C:19]=12)=[CH:31][CH:30]=[CH:29][CH:28]=4)=[O:26])[CH:12]=[CH:11][C:10]=3N)=[O:8].S1C=CC=C1C(Cl)=O>[N+](C1C=CC=CC=1)([O-])=O>[CH:1]1[CH:6]=[C:5]2[C:7]([C:9]3[CH:10]=[CH:11][CH:12]=[C:13]([NH:17][C:18]4[C:19]5[C:33]([C:32]6[C:27]([C:25](=[O:26])[C:20]=5[CH:21]=[CH:22][CH:23]=4)=[CH:28][CH:29]=[CH:30][CH:31]=6)=[O:34])[C:14]=3[C:15](=[O:16])[C:4]2=[CH:3][CH:2]=1)=[O:8]

参加物

4

反応物 2

HCID 789282-Thiophenecarbonyl chlorideHCID 178507708HCID 178507708、化合物

生成物 1

HCID 6700Anthrimide収率 145.4%

試薬・触媒・溶媒 1

HCID 7416Nitrobenzene溶媒

実験手順

9.2 g of 4,4'-diamino-1,1'-dianthrimide are heated in 75 ml of nitrobenzene to 145°-150° C. 6.5 g of thiophene-2-carboxylic acid chloride are then added dropwise over a period of 30 minutes. The temperature of the suspension is increased to 170°-175° C. over a period of 2 hours and the suspension is stirred for 2 hours at that temperature. After cooling, the product is filtered off and washed with nitrobenzene and ethanol. 12.5 g of the anthrimide of the formula (2) are obtained. The anthrimide is converted into the carbazole compound of the formula (1) in accordance with Example 1, paragraph 2.

後処理

  1. temperatureThe temperature of the suspension is increased to 170°-175° C. over a period of 2 hours
  2. temperatureAfter cooling
  3. filtrationthe product is filtered off
  4. washwashed with nitrobenzene and ethanol

出典と根拠

ORDレコード
ord-d0f4e1a4b9214e4f98160dd267039cb7
出典データセット
uspto-grants-1988_09
特許番号
US04772725

関連ノート

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