Methyl 3-hydroxypivalate → Methyl 3-(4-chloro-3-ethylphenoxy)-2,2-dimethylpropanoate

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[CH2:9][CH3:10].O[CH2:12][C:13]([CH3:19])([CH3:18])[C:14]([O:16][CH3:17])=[O:15]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:12][C:13]([CH3:19])([CH3:18])[C:14]([O:16][CH3:17])=[O:15])=[CH:4][C:3]=1[CH2:9][CH3:10]

参加物

反応物 2

HCID 84152Methyl 3-hydroxypivalate

HCID 842234-Chloro-3-ethylphenol

生成物 1

HCID 67973426Methyl 3-(4-chloro-3-ethylphenoxy)-2,2-dimethylpropanoate収率 85.3%

実験手順

By using 4-chloro-3-ethylphenol (2000 mg) and methyl hydroxypivalate (2025 mg), the procedure was carried out in the same manner as in Example 1-1) to obtain methyl 3-(4-chloro-3-ethylphenoxy)-2,2-dimethylpropanoate (2951 mg).

出典と根拠

ORDレコード: ord-7242994c442a44f38f680b42ff87e862
出典データセット: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09302996B2

反応ノート

読み込み中…